Valine

In IUPAC and IUB (1983) the systematic name is 2-amino-3-methylbutanoic acid, and its three-letter code is Val. The codons are GUU, GUC, GUA and GUG and the one – letter code is V, so Valines are three letter codes Val, V. Sources: 5

In biochemistry, the term “amino acid” is often used to refer specifically to alpha amino acids in which the amino carboxylate group is bound to the so-called carbon (alpha carbon) of an amino acid. The carbon structure is analogous to a branch of a tree, such as the tree of life, and the branches are the branch points that characterize the essential amino-acid carbon structures. L – Amino acid is the most common type of protein – it finds amino acid in the human body, but not the only one. Sources: 1, 5

All three amino acids are vital and particularly involved in stress, energy and muscle metabolism. Branched amino acids have different metabolic pathways, whereby valine flows exclusively into carbohydrates and fat and leucine into proteins. Sources: 1

These different metabolic processes explain the high levels of valine and leucine in the human body as well as the low levels in animals. Branched-chain amino acids are therefore essential for protein synthesis and muscle growth and are essentially anabolic substances that regulate the metabolism of carbohydrates, fat, proteins and other amino acid compounds. Chung and Baker (1992) described a study in which the valine deficiency was reduced by limiting the amino acid and was therefore crucial for muscle development and the development of muscle and bone growth in mice. Sources: 0, 1

As an essential amino acid, valine is not synthesized in animals and must normally be absorbed as a component of proteins. The amount needed by the animals increases with the amount of amino acids in the body due to the increase in protein synthesis and metabolism. Sources: 0, 5

It belongs to the so-called branched-chain amino acids (BCAAs) and is needed to maintain and repair muscle tissue. Amino acid acidopathy is a leading branch of the disease of amino acid deficiency in humans and other animals. Maple Syrup Urine Disease (MSUD) is the leading cause of kidney failure in adults and children in the United States. Sources: 5, 7

Studies have shown that valine and other BCAAs can prolong physical endurance in extreme heat and prevent muscle wastage at high altitudes. In addition, a study published in 1988 found that BCAA drugs helped patients with Lou Gehrig’s disease maintain muscle strength, but other studies have disproved this finding. While there is still research on the effects of branched-chain amino acids in improving exercise performance and the effect of physical exercise, these supplements are beneficial in the treatment of MSUD. Sources: 7

A is commonly used to relieve fatigue and improve athletic performance, and a recent review of eight studies found that supplementing with branch-chain amino acids is better than rest in promoting muscle recovery and reducing muscle soreness after exhausting exercise. In a study on resistance – exercising athletes, branch chains – the amino acid improved performance and muscle recovery and reduced muscle pain compared to a placebo [19]. Sources: 3

Taking 4 grams of leucine per day for 12 weeks increased strength and performance and showed that even non-athletes can benefit from this essential amino acid. Sources: 3

It has been found to prevent muscle loss and maintain lean body mass, as well as lowering blood pressure and cholesterol levels in the bodySources: 3

Studies on humans and animals have shown that the branching chain of this essential amino acid can stimulate fat loss. It has also been found to be able to maintain lean body mass in older people and athletes 23-24. A study in mice with high intake of the supplement and a placebo group showed that those who received 1,000 milligrams a day of a low-protein – high-fat – diet maintained muscle protein synthesis, a process that decreased by 30% in the placebo groups [22]. Sources: 3

In other words, valine is not only an essential amino acid, but also one of the most important amino acids in the body. In fact, it is so important that it has already been the subject of numerous studies on both humans and animals [23]. Sources: 6

There are 11 amino acids that need to be extracted as part of the daily diet because the body cannot synthesize them all. Some of them are crucial because they are used by our body to build proteins, but some of these amino acids cannot be produced by the body and we need to get them through food or supplements. If our body is unable to break them down and metabolize them, we can develop symptoms such as nausea, vomiting, diarrhoea, muscle pain, headaches, fatigue, nausea and even death. Sources: 4, 6

Valine is closely related in structure and function to leucine and isoleucines, but they share a characteristic chemical structure. These three amino acids are therefore known as branched-chain amino acids (BCAAs). Sources: 2, 4

Cited Sources

015 science 1 Honeystone LLC Fitness Supplements Boosters, Savin the Bees